Wouldn't obstruct replication, but it does give rise to an error in replication, so that the newly formed DNA strand carries with it a mutation.
Bring Back The Tapes, My Hexagonal Pencil Is Useless! Enthropy / Game / Replicant by 4dm1n_4rk4d14 08/06/2018
It would be possible to describe everything scientifically, but it would make no sense, it would be without meaning, as if you described a Beethoven symphony as a variation of wave pressure.